Abstract
The synthesis of a series of aminoethylbiphenyls as novel 5-HT(7) receptor ligands is described. The novel derivatives exhibit high affinity for the 5-HT(7) receptor with selectivity toward 5-HT(1A) receptor.
MeSH terms
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Aminobiphenyl Compounds / chemical synthesis
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Aminobiphenyl Compounds / chemistry*
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Aminobiphenyl Compounds / pharmacology
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Animals
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Humans
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Ligands
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Rats
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Receptors, Serotonin / chemistry*
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Receptors, Serotonin / drug effects
Substances
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Aminobiphenyl Compounds
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Ligands
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Receptors, Serotonin
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serotonin 7 receptor